Cadrol bisoprolol fumarate
tablet USP 5mg
Generic Manufacturer – Taj Pharmaceuticals
Each Cadrol 2.5 mg/6.25 mg tablet contains:
Bisoprolol fumarate...................................................2.5 mg
Each Cadrol 5 mg/6.25 mg tablet contains:
Bisoprolol fumarate...................................................5 mg
Each Cadrol 10 mg/6.25 mg tablet contains:
Bisoprolol fumarate..................................................10 mg
 Inactive ingredients include Colloidal Silicon Dioxide, Corn Starch, Dibasic Calcium Phosphate, Hypromellose, Magnesium Stearate, Microcrystalline Cellulose, Polyethylene Glycol, Polysorbate 80, and Titanium Dioxide. The 5 mg/6.25 mg tablet also contains Red and Yellow Iron Oxide. The 2.5 mg/6.25 mg tablet also contains Crospovidone, Pregelatinized Starch, and Yellow Iron Oxide.
INDICATIONS
Cadrol (bisoprolol fumarate and hydrochlorothiazide) is indicated in the management of hypertension. It combines two antihypertensive agents in a once-daily dosage: a synthetic beta1-selective (cardioselective) adrenoceptor blocking agent (bisoprolol fumarate) and a benzothiadiazine diuretic (hydrochlorothiazide).
USES
This combination medication is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
This product contains two medications. Bisoprolol is a beta blocker that works by blocking the effect of certain natural chemicals (e.g., epinephrine) on the heart and blood vessels. This slows your heartbeat, lowers blood pressure, and reduces strain on the heart. Hydrochlorothiazide is a "water pill" (diuretic) that works by increasing the amount of urine that you make. This causes your body to get rid of extra salt and water, which probably helps to relax the blood vessels so that blood can flow more easily. These two drugs are used together when one medication is not controlling your blood pressure. Using these two drugs together can also reduce the amount of each drug you must take, thereby decreasing the chances of side effects.
DOSAGE AND ADMINISTRATION
Bisoprolol is an effective treatment of hypertension in once-daily doses of 2.5 to 40 mg, while hydrochlorothiazide is effective in doses of 12.5 to 50 mg. In clinical trials of bisoprolol/hydrochlorothiazide combination therapy using bisoprolol doses of 2.5 to 20 mg and hydrochlorothiazide doses of 6.25 to 25 mg, the antihypertensive effects increased with increasing doses of either component.
WARNINGS
Cardiac Failure: In general, beta-blocking agents should be avoided in patients with overt congestive failure. However, in some patients with compensated cardiac failure, it may be necessary to utilize these agents. In such situations, they must be used cautiously.
PRECAUTIONS
General
Electrolyte and Fluid Balance Status: Although the probability of developing hypokalemia is reduced with Cadrol because of the very low dose of HCTZ employed, periodic determination of serum electrolytes should be performed, and patients should be observed for signs of fluid or electrolyte disturbances, ie, hyponatremia, hypochloremic alkalosis, hypokalemia, and hypomagnesemia. Thiazides have been shown to increase the urinary excretion of magnesium; this may result in hypomagnesemia.
Parathyroid Disease
Calcium excretion is decreased by thiazides, and pathologic changes in the parathyroid glands, with hypercalcemia and hypophosphatemia, have been observed in a few patients on prolonged thiazide therapy.
CONTRAINDICATIONS
Cadrol is contraindicated in patients in cardiogenic shock, overt cardiac failure (see WARNINGS), second or third degree AV block, marked sinus bradycardia, anuria, and hypersensitivity to either component of this product or to other sulfonamide-derived drugs.
Presentation
Cadrol Tablets Blister of 10 Tablets
Our number one priority at Generic Manufacturing is to build innovative and useful packaging, quality and manufacturing drugs according to the customer's specifications. We can customize one batch of Generic Medicine or an entire set of products.
Taj Pharmaceuticals Ltd. is a Pharmaceutical Generic manufacturer of Bisoprolol and manufacturer of various pharmaceutical formulations in India. Taj Pharmaceuticals Ltd. provide different pharmaceutical brands and Generic Medicines
The generic manufacturing strategies of New Drug (Bisoprolol) and the product-process of Taj Pharmaceuticals Ltd. are compared and collaborated using data from global Pharmaceuticals manufacturing plants in the UK(Newcastle), US, Korea, Italy, Germany and Japan.
We are an eminent manufacturer, supplier and exporter of Bisoprolol and various pharmaceuticals generics medicines in Tablets, capsules, Vial (injections), ampule, Strips and schedule packs etc.
Bisoprolol and different pharma Tablet & Capsule formulations are also available in different drug delivery forms. We also have large volume manufacturing facilities for these Products.
With over two decades of experience, we, Taj Pharmaceuticals Ltd., are one of the leading generic pharmaceutical companies. We believe that access to quality healthcare is a right, and not a privilege. Therefore, we endeavor to ensure the availability of world class, quality medicines at affordable prices across the globe.
We are committed to work towards a healthier and happier world. The company is an integrated, research based international pharmaceutical company, producing a wide range of quality, affordable generic (Bisoprolol) medicines, trusted by health-care professionals and patients across geographies.
We offer you the highest quality new Generic medicines ie. Bisoprolol, drugs and also with innovative packing at the lowest prices shipped to you from India. Browse our latest Pharmaceuticals and Generics possibilities and other pharmaceuticals possibilities…more.
Generic Manufacturer – Taj Pharmaceuticals
Our number one priority at Generic Manufacturing is to build innovative and useful packaging, quality and manufacturing drugs according to the customer's specifications. We can customize one batch of Generic Medicine or an entire set of products.
Taj Pharmaceuticals Ltd. is a Pharmaceutical Generic manufacturer of Bisoprolol and manufacturer of various pharmaceutical formulations in India. Taj Pharmaceuticals Ltd. provide different pharmaceutical brands and Generic Medicines
The generic manufacturing strategies of New Drug (Bisoprolol) and the product-process of Taj Pharmaceuticals Ltd. are compared and collaborated using data from global Pharmaceuticals manufacturing plants in the UK(Newcastle), US, Korea, Italy, Germany and Japan.
We are an eminent manufacturer, supplier and exporter of Bisoprolol and various pharmaceuticals generics medicines in Tablets, capsules, Vial (injections), ampule, Strips and schedule packs etc.
Bisoprolol and different pharma Tablet & Capsule formulations are also available in different drug delivery forms. We also have large volume manufacturing facilities for these Products.
With over two decades of experience, we, Taj Pharmaceuticals Ltd., are one of the leading generic pharmaceutical companies. We believe that access to quality healthcare is a right, and not a privilege. Therefore, we endeavor to ensure the availability of world class, quality medicines at affordable prices across the globe.
We are committed to work towards a healthier and happier world. The company is an integrated, research based international pharmaceutical company, producing a wide range of quality, affordable generic (Bisoprolol) medicines, trusted by health-care professionals and patients across geographies.
We offer you the highest quality new Generic medicines ie. Bisoprolol, drugs and also with innovative packing at the lowest prices shipped to you from India. Browse our latest Pharmaceuticals and Generics possibilities and other pharmaceuticals possibilities…more.
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